High Pressure Homogenizer
We provide a wide range of high pressure homogenizers
High pressure homogenizer
Product Details:
- Product Type: High pressure Homogenizer
- General Use: Food industry
- Material: Stainless Steel
- Type: Fluids Grinding Machine
- Computerized: No
- Automatic : No
- Power： Up to 200kw
Product Description
High pressure homogenizers, also known as “high pressure fluid nano-homogenizers,” allow suspensions to flow at high speeds through a specially structured cavity (high-pressure homogenization chamber) under ultra-high pressure (up to 60,000 psi), causing a series of physical, chemical, and structural changes in the material, ultimately achieving homogenization. Standard homogenizers operate at pressures up to 15,000 psi, high-pressure homogenizers up to 30,000 psi, and ultra-high-pressure homogenizers up to 60,000 psi.
High pressure homogenizers are primarily used in the biological, pharmaceutical, food, and chemical industries for cell disruption, beverage homogenization, fine chemical processing, and the preparation of liposomes, fat emulsions, nano-suspensions, micro emulsions, lipospheres, vaccines, emulsions, dairy products, large-volume parenteral solutions, dyes, graphene carbon nanotubes, conductive coatings, and the dispersion of nano-oxides. The international market size in this field exceeds 10 billion yuan. The production of pharmaceutical emulsions requires ultra-high pressure homogenizers, with pressures at least 20,000 psi and high-quality diamond interactive homogenizing chambers to achieve a uniform and safe pharmaceutical-grade particle size distribution. Currently, the high pressure homogenizers used in the domestic pharmaceutical industry are almost entirely imported.
High pressure homogenizer Structure Principle and Features
The high pressure homogenizer mainly consists of a high-pressure homogenizing chamber and a pressurizing mechanism. The diamond inside the high-pressure homogenizing chamber has specially designed geometrically shaped micropores. Under the action of the pressurizing mechanism, the high-pressure solution passes through the homogenizing chamber at supersonic speed. The material is simultaneously subjected to mechanical forces such as high-speed shearing, high-frequency oscillation, cavitation, and convective impact, as well as corresponding thermal effects. The resulting mechanical and chemical effects induce changes in the physical, chemical, and particle structure properties of the material macromolecules, forming a more uniform particle size and evenly distributed in the solution, ultimately achieving homogenization.
Pressure Boosting Principle
Mechanical Type
The motor drives the crankshaft to reciprocate the plunger, directly pressurizing the material. Multiple sets of plungers provide continuous pressure, resulting in high homogenization pressure and large output. However, the minimum material quantity is relatively large, leading to a larger residue. Furthermore, the motor-driven crankshaft requires a multi-stage reduction mechanism, resulting in lower equipment efficiency and a larger size. Suitable for food, chemical, and low-pressure applications.
Hydraulic Type
The hydraulic type is a recent development in ultra-high pressure technology. The motor drives an oil pump, pressurizing the material through a hydraulic system. The hydraulic system can provide higher pressure, resulting in higher equipment efficiency, a relatively smaller size, and a smaller minimum material quantity. Suitable for both experimental and production applications. Hydraulic homogenizers are expensive, but hydraulic boosting allows for low-speed, high-thrust piston movement, increasing machine lifespan and reducing maintenance costs. Parallel four-cylinder technology, used in high-pressure homogenizers, provides stable pressure without the need for an accumulator. Hydraulic operation can achieve ultra-high pressures of 45,000 psi.
Maximum Homogenization Pressure
Generally, higher homogenization pressure is better. Firstly, higher homogenization pressure results in smaller and more uniform particle sizes after homogenization. This increases equipment efficiency, allowing for fewer cycles to achieve the desired effect. Secondly, higher homogenization pressure allows for the processing of a wider variety of materials. For example, some liquid emulsions can be homogenized to below 100nm at 20,000 psi, while some suspensions containing high-density solid particles require at least 45,000 psi to reach the nanoscale.
However, it’s important to note that higher homogenization pressure generates more heat, which can negatively impact homogenization. Therefore, 30,000 psi is generally the maximum pressure for ultra-high pressure homogenization without cooling measures. Due to the high temperatures generated by ultra-high pressure homogenizers, homogenization efficiency does not improve beyond 30,000 psi. The development of temperature-controlled ultra-high pressure diamond-coated interlocking chambers effectively reduces the large particle content and emulsion stability issues caused by high temperatures, enabling high-pressure homogenization to reach 60,000 psi.
Applications Across Industries
High pressure homogenizers are one of the most effective production equipment for preparing nanomaterials using top-down nanotechnology processes. Their applications are very wide-ranging, with a global market demand of nearly 10 billion RMB.
● In the pharmaceutical industry, it is used to prepare fat particles, microemulsions, liposomes, nanosuspensions, nanoparticles, and microcapsules;
● In bioengineering products, it is used for cell disruption, microemulsions, and liposome-type adjuvants;
● In the food and beverage industry, it is used for homogenization and emulsification to improve product stability, taste, appearance, and effective nutrient encapsulation;
● In the cosmetics and fine chemical industries, it is used for homogenization and dispersion to enhance functionality, differentiate products, increase added value, and ensure process stability;
● It is used for the dispersion and exfoliation of conductive pastes, resistive pastes, graphene, carbon nanotubes, and nano-oxides.
| Model | Capacity(L/H) | Power (KW) | Maximum Pressure (Mpa) | Outline Dimension (mm) |
|---|---|---|---|---|
| NLH1000-45 | 1000 | 15 | 45 | 1400-900-950 |
| NLH2000-45 | 2000 | 30 | 45 | 1450-1000-1100 |
| NLH3000-40 | 3000 | 37 | 40 | 1650-1150-1200 |
| NLH5000-50 | 5000 | 75 | 50 | 1950-1250-1450 |
| NLH6000-50 | 6000 | 90 | 50 | 2150-1550-1550 |
| NLH8000-30 | 8000 | 75 | 30 | 1950-1250-1450 |
| NLH10000-30 | 10000 | 90 | 30 | 2150-1550-1550 |
| NLH15000-40 | 15000 | 200 | 40 | 2250-2000-1500 |
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